Search on: HEPATOCYTE NUCLEAR FACTORS 
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Descriptor English:   Hepatocyte Nuclear Factors 
Descriptor Spanish:   Factores Nucleares del Hepatocito 
Descriptor Portuguese:   Fatores Nucleares de Hepatócito 
Tree Number:   D12.776.260.262
D12.776.660.352
D12.776.930.323
Definition English:   Hepatocyte nuclear factors are a family of evolutionarily conserved transcription factors that are preferentially expressed in HEPATOCYTES. They play important roles in liver-specific transcription and are critical for CELL DIFFERENTIATION and METABOLISM. 
Indexing Annotation English:   general; prefer specifics
History Note English:   2006 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   50995 
Unique Identifier:   D051536 

Occurrence in VHL: 		 

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